생리식염수 세척이 구강 소독제의 타액 내 세균 수의 변화에 미치는 영향

김동주; 유경환; 임형섭; 이성규; 김수관; 김학균

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생리식염수 세척이 구강 소독제의 타액 내 세균 수의 변화에 미치는 영향
Effect of saline irrigation used in combination with antimicrobial agents on salivary bacterial counts

대한구강악안면외과학회지 2010년 36권 3호 p.202 ~ 205

김동주, 유경환, 임형섭, 이성규, 김수관, 김학균,

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김동주 ( Kim Dong-Joo ) - 조선대학교 치과대학 구강악안면외과학교실
유경환 ( Yu Kyoung-Hwan ) - 조선대학교 치과대학 구강악안면외과학교실
임형섭 ( Lim Hyong-Sup ) - 조선대학교 치과대학 구강악안면외과학교실
이성규 ( Lee Sung-Kyu ) - 조선대학교 치과대학 구강악안면외과학교실
김수관 ( Kim Su-Gwan ) - 조선대학교 치과대학 구강악안면외과학교실
김학균 ( Kim Hak-Kyun ) - 조선대학교 치과대학 구강악안면외과학교실

KMID : 0355620100360030202

Abstract

Introduction: The aim of the present study was to investigate the effect of mechanical irrigation in combination with mouthwash of antimicrobial agents on salivary bacterial counts.

Materials and Methods: This study was performed with a randomized study employing a panel of 40 healthy volunteers (20 males and 20 females) between the age of 26 and 32 years. Volunteers were randomly put in one of four treatment groups. In the first group, 0.2 mL of non-stimulatory saliva was collected from every subjective person. Then, saliva was collected after rinsing with chlorhexidine (CHX) for 1 minute. In the second group, nonstimulatory saliva was collected, and then saliva was collected after rinsing with CHX and irrigation with saline. In the third and fourth groups, the same procedures as the first and second groups were performed with povidone iodine (PVI) instead of CHX. All of these samples were cultured for 48 hours aerobically. The reduction rates of colony-forming units (CFU) were calculated for each group. The reduction rate between each group was tested statistically using student t-test.

Results: Using CHX in combination with saline irrigation showed a significant decrease of the salivary bacterial CFU when compared with only using CHX.(P＜0.01) And using PVI with saline irrigation showed a little decrease of the CFU when compared with only using PVI, but there was no statistical significance.(P＞0.01)

Conclusion: It was concluded that the CHX or PVI used with saline irrigation made the salivary bacterial counts reduced more than when CHX or PVI was used alone as an oral antiseptic agent.